Jump to the main content block
CME Logo
 
 

標題

✕
 
  1. Home
  2. Faculty
  3. Professor

Yi-Fan Chen, Professor

Yi-Fan Chen - Professor
陳儀帆 教授
2003 B.S. in Chemical Engineering, National Taiwan University
2011 Ph.D. in Physics, Cornell University, USA (2011; advisor: Sol Gruner)
Ext.: 34237
Office: Engineering Building 1, E237A
Lab: Biological and Soft Matter Physical Chemistry Laboratory - Engineering Building 1, E232
Email: yifanchen@ncu.edu.tw
Professor Yi-Fan Chen Photo

Research Interests

Characterization of soft materials, Biophysics, Soft condensed matter / Biological liquid crystals, Applications of X-ray scattering and single-crystal diffraction, Applications of high-pressure physics.

We are dedicated to applying scattering and crystal diffraction techniques using synchrotron radiation and neutron sources, combined with high-pressure physics methods, to investigate the structure, dynamics, and phase transition behaviors of lyotropic liquid crystals and biological soft matter. From this research, we aim to establish the correlation between function, structure, and dynamics of materials. This correlation not only enhances our fundamental understanding of these material systems (of interest to scientists) but also aids in the design and development of functional materials (a goal for engineers). Current research topics include:

1. Phase transition mechanisms of electrically charged phospholipids and other lyotropic liquid crystals.

2. Correlation between material properties and dynamic properties of lipid biomembranes.

3. Development of high-pressure cryocooling techniques for protein crystallization and design of other scientific instruments.

4. Interaction between water and biological soft matter.

5. Application of neutron scattering techniques in biological and novel material systems.

We welcome graduate and undergraduate students interested in the above research topics. We also seek potential collaboration opportunities with research teams interested in the structural and dynamic characterization of biological and material systems.

Publications

  1. Hsieh, T. -Y., Mansel, B. W., Chen, H. -L., Chen, Y. -F. 2025 "Drastic Elevation in the Glass Transition Temperature of Poly(2-vinylpyridine) by the Entanglement-Promoting Palladium Nanoparticles." Macromolecules, Volume 58, 2336.

  2. Lu, Y. -H., Chang, B. K., Chen, Y. -F. 2025 "Electronic Structure Modulation from Configuring Anatase TiO2 into a Bicontinuous Mesostructure." Journal of the Taiwan Institute of Chemical Engineers, Volume 167, 105829 (preprint: arXiv:2310.13306).

  3. Ko, T. H. & Chen, Y.-F. 2023 "Correlation between the In-plane Critical Behavior and Out-of-plane Interaction of Ternary Lipid Membranes." Membranes, Volume 13, 6.

  4. Chang, S. -M., et. al. 2022 "Mechanism of endosomal escape by pH-responsive nucleic-acid vectors." Physical Review E, Volume 106, 034408.

  5. Chiou, P. -C., et. al. 2022 "Molecular packing of lipid membranes and action mechanisms of membrane-active peptides." Colloids and Surfaces B: Biointerfaces, Volume 213, 112384.

  6. Huang, Y. -J., et. al. 2021 "In-Situ Synchrotron SAXS and WAXS Investigation on the Deformation of Single and Coaxial Electrospun P(VDF-TrFE)-Based Nanofibers." Internationa Journal of Molecular Sciences, Volume 22, 12669.

  7. Xie, C. -Z., et. al. 2020 "Uncoupling between the lipid membrane dynamics of differing hierarchical levels." Physical Review E, Volume 101, 012416.

  8. Lee, Y. -P., et. al. 2019 "Long-term thermally stable nanoconfining networks for efficient fully T conjugated semicrystalline/amorphous diblock copolymer photovoltaics." Organic Electronics, Volume 69, p263-274.

  9. Chang, W. -F., et. al. 2018 "Correlation of an antimicrobial peptide’s potency and its influences on membrane elasticity." Physical Review E, Volume 98, 042408.

  10. Tsai, C. -W., et. al. 2018 "Development of an indolicidin-derived peptide by reducing membrane perturbation to decrease cytotoxicity and maintain gene delivery ability." Colloids and Surfaces B: Biointerfaces, Volume 165, 18.

  11. Tsang, K. -Y., et. al. 2017 "Coupling of lipid membrane elasticity and in-plane dynamics." Physical Review E, Volume 96, 012410.

  12. Muduli, S., et. al. 2017 "Proliferation and osteogenic differentiation of amniotic fluid-derived stem cells." Journal of Materials Chemistry B, Volume 5, 5345.

  13. Fan, Z. -A., et. al. 2016 "Revisit the Correlation between the Elastic Mechanics and Fusion of Lipid Membranes." Scientific Reports (Nature Publishing Group), Volume 6, 31470.

  14. Chen, Y. -F.*, et. al. 2015. "Differential Dependences on [Ca2+] and Temperature of the Monolayer Spontaneous Curvatures of DOPE, DOPA and Cardiolipin: Effects of Modulating the Strength of the Inter-headgroup Repulsion." Soft Matter, Volume 11, p4041-4053.

  15. Liu, C. Y., et. al. 2014. "PEGylation Site-Dependent Structural Heterogeneity Study of MonoPEGylated Human Parathyroid Hormone Fragment hPTH(1-34)." Langmuir, Volume 30, p11421-11427.

  16. Lee, Y. H., et. al. 2014. "Phase transformation and self-assembly behavior of supramolecular rod comb block copolymers." Polymer, Volume 55, p2481-2490.

  17. Lee, Y. H., et. al. 2014. "A new strategy for co-assembling pi-conjugated polymer/cadmium sulfide hybrids into an efficient charge-transporting nanochannel array by using an all-conjugated diblock copolymer motif." Journal of Materials Chemistry A, Volume 2, p14600-14612.

  18. Lai, Y. -C.; Chen, Y. -F.; Chiang, Y. -W. 2013. "ESR Study of Interfacial Hydration Layers of Polypeptides in Water-Filled Nanochannels and in Vitrified Bulk Solvents." PLoS ONE, Volume 8, e68264.

  19. Yu, C. F.; Chao, D. S.; Chen, Y. -F.; Liang, J. H. 2013. "Photoluminescent Characteristics of Ion Beam Synthesized Ge Nanoparticles in Thermally Grown SiO2 Films." Nuclear Instruments & Methods in Physics Research B, Volume 307, p171-176.

Click Num: